- Scout Island
- Sea Pines
- Sea Pines Circle
- Sea Pines Plantation
- Seabrook
- Seabrook Landing
- Sheep Island
- Shell Point park
- Shelter Cove
- Shepherd Island
- Sherwood Forest
- Shipyard Plantation
- Skid Island
- South Beach Villas
- Spanish Wells
- Spring Island
- Springfield
- Sandy Run
- Singleton
- Staley Crossroads
- Saint Andrews
- Sandy
- Scanawah Island
- Scanlonville
- Seaside
- Seaside Farms Estates
- Secessionville
- Secessionville Acres
- Shadowmoss
- Shiloh